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Air embolism is a serious complication of catheterization and may cause mortality and morbidity. Currently, there is no used for air embolism prevention during angiography and angioplasty procedures. In this study, we tested the flow dynamics and efficiency of a new air holder device in virtual hemodynamic conditions.
Our study focused on optimizing the geometry of a Left Ventricular Assist Device (LVAD) to enhance blood flow while minimizing shear-induced damage to blood cells. Various designs were analyzed through computational fluid dynamics (CFD) simulations, evaluating wall shear stress distribution and flow efficiency. The objective was to identify a geometry that ensures sufficient perfusion at a lower Reynolds number regime while reducing the risk of hemolysis. This research contributes to the development of safer and more efficient LVAD designs for patients requiring cardiac support.
Artificial liver systems have gained significant attention as potential solutions for temporary liver support, particularly in cases of acute liver failure. These systems often rely on membrane-based bioreactors to facilitate mass transfer between blood plasma and a biological component, mimicking natural liver functions. In this study, we investigate the impact of membrane permeability on the flow conditions within a bi-flow system, where two fluid streams interact through a porous membrane in an artificial liver cell model. The permeability of the membrane plays a crucial role in determining the efficiency of mass transport, shear stress distribution, and overall fluid dynamics within the system. By employing computational fluid dynamics (CFD) simulations and experimental validation, this research aims to optimize membrane properties to enhance performance, ultimately contributing to the development of more effective bioartificial liver devices.